Ok here is my setup. Like I said, It's wierd, but It's what I'm used to.
I number my hotbars from bottom to top, and then have 2 more on the right side. (Note, this is taken from my work computer, but still very much similar to my home setup, but with a different UI.)
So my first hotbar (Bottom) is my basic rotation, not including a few abilities I kinda refer to as "Starters". My starters are Lightning Fist, Masters Strike, Pressure Point, and Claw, Kerran racial mit debuff. My Starters are actually on hotbar 4. DOnt ask me why they are there, they just are, it's probably because I didn't always have those abilities so eventually had to make room.
2nd hotbar is FD and Heal, then all my taunts, and then my AoEs.
3rd is buffs, and then the old school temps on the right, (Close mind etc).
4th is my max dps temps on the left, my "starters" in the middle, and some extras on the right (Brocks, Manastone, LoN Mana and HP potion).
5th is wierd. 1st 2 are macros, one that changes from fight to fight, and the second changes alot also, but currently it's for re-equipping a wrist item right after I activate lycanthrope wrist. Then I have some of the more recent defensive temps, mythical, Cyclone off-hand clicky, charm clicky for when I have quellios charm up. Then control hate, (Just because... I rarely have to use it but it's got it's own spot.) Then Kerra Racials and finally sprint.
Right side top - Just macros, Sonic Punch, and Mez.
Right Side Bottom - more macros, potions, temp adorns. Oh, and Mid stance... not sure how that ended up there but there it is.
Like I said my hotbars are wierd.